Hepatitis C Virus Infection

  • Freedom from injecting Interferon (IFN), treating major HCV genotypes WW and betting on vaccines could bring a sea of change in the treatment of HCV infection in the future. This year the first IFN-free drug options for HCV Genotype 2/3- Gilead’s Sofosbuvir/RBV (GS-7977, PDUFA Dec. 8, 2013) is expected to be approved and launched! By 2015 launch of Gilead’s Sofosbuvir/Ledipasvir (PhIII) and AbbVie/ Enanta’s (ABT-450r/ABT-472/ABT-333) should remove the need of IFN for GT1 genotype HCV patients as well!

    Tapping the Bigger Market- ROW: Gilead is moving well towards offering the best treatment options to a broader HCV pt population WW. . Genotype 1 is common in Australia, China, Taiwan and other countries in North Asia, while genotype 6 is found in Vietnam and other Southeast Asian countries. In India and Pakistan, genotype 3 is predominant, while genotype 4 is found in Middle Eastern countries such as Egypt, Saudi Arabia and Syria. A PAN genotype effective drug is what most companies are trying to sequester in their pipeline. This report comprehensively covers the current Standard of Care, its limitations and Future options for the treatment of HCV infection.

     

  • With tables and figures helping analyze worldwide Hepatitis C Virus Infection market, this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.


    1.Executive Summary

    2.Progress in the Clinical Development of HCV drugs
    •Noteworthy progress in the Oral IFN –Free combinations for Treatment of HCV
    •Options for the most Challenging Patient Subtypes in HCV
    •IFN intolerant and other Genotypes
    •Hepatitis C Virus Prevalence in ROW

    3.Competitive Landscape - IFN-Free drugs
    •Gilead’s sofosbuvir/ ledipasvir
    •AbbVie’ ABT-450r/ABT-472/ABT-333
    •Boehringer Ingelheim’s faldaprevir/BI 207127
    •Medevir’s simeprevir
    •Vertex’s VX-135
    •Bristol Myers’ daclatasvir/asunaprevir
    •Merck- MK-5172/MK-8742

    4.Market Dynamics- Present and Future
    •Present- Launch of Protease Inhibitors: Sunset Sooner Than Expected.
    •Future- the “best-in-class IFN-free oral pill” for HCV

    5.HCV Vaccines
    •GlobeImmune
    •Okairos
    •ChronTech Pharma/ Inovio
    •Transgene’s TG4040
    •Profectus Biosciences’ HCV vaccine
    •Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden

    6.HCV-HIV Co infection
    •Pricing
    •Market share dynamics

    7.ANNEXURE
    •Key Milestones
    •Table 1 - Data from IFN-free combinations
    •Table 2 - Viral response in genotype-1 patients – IFN-combinations
    •Key Abstract presented at AASLD ‘13

     

  • The Hepatitis C Virus Infection Market has been segregated into various crucial divisions including applications, types, and regions. Each market segment is intensively studied in the report contemplating its market acceptance, worthiness, demand, and growth prospects. The segmentation analysis will help the client to customize their marketing approach to have a better command of each segment and to identify the most prospective customer base.

    Report Objectives / Segmentation Covered :
    By Companies / players:
      By Regions:
        By Type:
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          Research objectives

          Where will all these developments take the industry in the long

          To study and analyze the global Market consumption (value & volume) by key regions/countries, product type and application, history data from 2015 to 2019, and forecast to 2025.

          What are the future opportunities in the market?

          To understand the structure of Market by identifying its various subsegments.

          What are the major driving forces expected to impact the development of the market market across different regions?

          To analyze the market with respect to individual growth trends, future prospects, and their contribution to the total market.

          Which industry trends are likely to shape the future of the industry during the forecast period 2020-2025?

          To project the consumption of market submarkets, with respect to key regions.

          Who are the major driving forces expected to decide the fate of the industry worldwide.

          To strategically profile the key players and comprehensively analyze their growth strategies.

          What are the key barriers and threats believed to hinder the development of the industry?

          To analyze competitive developments such as expansions,agreements, new product launches, and acquisitions in the market.

          Who are the prominent market players making a mark in the market with their winning strategies?

          To share detailed information about the key factors influencing the growth of the market

          What will be the growth rate and the market size of the industry for the forecast period 2020-2025?

          Focuses on the key global market Vendors, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.

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